What TXA dosing regimen is listed for postpartum hemorrhage?

What TXA dosing regimen is listed for postpartum hemorrhage?

• A. 2 g IV bolus over 5 minutes
• B. 2 g IV bolus over 1 hour
• C. 1 g IV over 10 minutes
• D. 2 g in 100 ml, 10 drop-set, 3 drops a second over 5 min

Answer: (D)

Tranexamic acid helps stop postpartum hemorrhage by blocking the breakdown of clots, so delivering the full dose quickly is important. The option that describes 2 g in 100 mL given by IV infusion over about 5 minutes using a standard drop-set (3 drops per second) provides the full 2 g rapidly in a controlled infusion, which is why it’s listed as the regimen. The other choices either give the dose too fast as a bolus, too slow, or deliver only 1 g, which doesn’t match this dosing pattern.

Tranexamic acid helps stop postpartum hemorrhage by blocking the breakdown of clots, so delivering the full dose quickly is important. The option that describes 2 g in 100 mL given by IV infusion over about 5 minutes using a standard drop-set (3 drops per second) provides the full 2 g rapidly in a controlled infusion, which is why it’s listed as the regimen. The other choices either give the dose too fast as a bolus, too slow, or deliver only 1 g, which doesn’t match this dosing pattern.