What is the maximum single dose of amiodarone for pediatric cardiac arrest?

What is the maximum single dose of amiodarone for pediatric cardiac arrest?

• A. 300 mg
• B. 150 mg
• C. 450 mg
• D. 600 mg

Answer: (A)

Amiodarone dosing in pediatric cardiac arrest is weight-based, with a safety cap on a single bolus. The recommended amount is 5 mg per kilogram given IV or IO for a shock-refractory rhythm (ventricular fibrillation or pulseless ventricular tachycardia). To protect smaller patients from adverse effects, there is a maximum for one dose, which is 300 mg. If the rhythm persists, a second dose of the same amount can be given, but the total should stay within about 15 mg/kg (roughly up to 450 mg in many guidelines). So the reason 300 mg is the best answer is that it sets the upper limit for a single amiodarone bolus in pediatric cardiac arrest, balancing effectiveness with safety.

Amiodarone dosing in pediatric cardiac arrest is weight-based, with a safety cap on a single bolus. The recommended amount is 5 mg per kilogram given IV or IO for a shock-refractory rhythm (ventricular fibrillation or pulseless ventricular tachycardia). To protect smaller patients from adverse effects, there is a maximum for one dose, which is 300 mg. If the rhythm persists, a second dose of the same amount can be given, but the total should stay within about 15 mg/kg (roughly up to 450 mg in many guidelines). So the reason 300 mg is the best answer is that it sets the upper limit for a single amiodarone bolus in pediatric cardiac arrest, balancing effectiveness with safety.