In pediatric post‑intubation sedation/paralysis, which drug is dosed at 1 mg/kg (diluted) IV/IO?

In pediatric post‑intubation sedation/paralysis, which drug is dosed at 1 mg/kg (diluted) IV/IO?

• A. Rocuronium 1 mg/kg IV/IO
• B. Ketamine 1 mg/kg (Diluted) IV/IO
• C. Fentanyl 1 mcg/kg (Diluted) IV/IO SLOW push
• D. Etomidate 0.3 mg/kg

Answer: (B)

In pediatric post‑intubation sedation/paralysis, you want an agent that can rapidly provide sedation and analgesia while keeping the airway management straightforward. Ketamine given at about 1 mg/kg IV/IO fits this need. When diluted for IV/IO administration, this dose allows a controlled, rapid onset effect that provides both sedation and analgesia, with the added benefits of bronchodilation and relatively stable cardiovascular tone. These properties make it a practical, effective choice in the post‑intubation setting. Other drugs listed have different standard uses or dosing patterns: fentanyl is given around 1 mcg/kg (not 1 mg/kg) and is an analgesic; etomidate is typically dosed at about 0.3 mg/kg for induction; rocuronium is a paralytic dosed at 1 mg/kg but is not used for sedation and is not typically described as “diluted” in this specific context.

In pediatric post‑intubation sedation/paralysis, you want an agent that can rapidly provide sedation and analgesia while keeping the airway management straightforward. Ketamine given at about 1 mg/kg IV/IO fits this need. When diluted for IV/IO administration, this dose allows a controlled, rapid onset effect that provides both sedation and analgesia, with the added benefits of bronchodilation and relatively stable cardiovascular tone. These properties make it a practical, effective choice in the post‑intubation setting.

Other drugs listed have different standard uses or dosing patterns: fentanyl is given around 1 mcg/kg (not 1 mg/kg) and is an analgesic; etomidate is typically dosed at about 0.3 mg/kg for induction; rocuronium is a paralytic dosed at 1 mg/kg but is not used for sedation and is not typically described as “diluted” in this specific context.