In pediatric beta blocker overdose for a child weighing more than 20 kg, what is the recommended glucagon dose IV/IO?

In pediatric beta blocker overdose for a child weighing more than 20 kg, what is the recommended glucagon dose IV/IO?

• A. 0.5 mg
• B. 2 mg
• C. 5 mg
• D. 1 mg

Answer: (D)

Glucagon helps in beta-blocker overdose by activating glucagon receptors in the heart, increasing the cAMP signal and boosting heart rate and contractility independent of blocked beta receptors. For a child weighing more than 20 kg, the initial glucagon dose given IV or IO is 1 mg as a bolus. This fixed dose provides a rapid, reliable inotropic and chronotropic effect in this weight range. If the response is incomplete, clinicians may repeat the bolus after a few minutes or proceed with protocol-directed infusion, but the starting dose is 1 mg.

Glucagon helps in beta-blocker overdose by activating glucagon receptors in the heart, increasing the cAMP signal and boosting heart rate and contractility independent of blocked beta receptors. For a child weighing more than 20 kg, the initial glucagon dose given IV or IO is 1 mg as a bolus. This fixed dose provides a rapid, reliable inotropic and chronotropic effect in this weight range. If the response is incomplete, clinicians may repeat the bolus after a few minutes or proceed with protocol-directed infusion, but the starting dose is 1 mg.