In Adult Cardiac Arrest V-Fib/V-Tach, what is the initial amiodarone dose?

In Adult Cardiac Arrest V-Fib/V-Tach, what is the initial amiodarone dose?

• A. 300 mg (1st dose)
• B. 150 mg (1st dose)
• C. 100 mg (1st dose)
• D. 450 mg (1st dose)

Answer: (A)

In adults, when ventricular fibrillation or pulseless VT persists after defibrillation attempts, amiodarone is given as a IV/IO bolus to help stabilize the rhythm by blocking multiple channels and prolonging the heart’s refractory period. The initial dose is 300 mg. If the rhythm remains shockable after additional shocks, a second dose of 150 mg can be given, for a total of up to 450 mg during the arrest. The other listed amounts aren’t the first-dose amount (150 mg is the second-dose amount, 100 mg isn’t standard, and 450 mg reflects the possible total after two doses, not the initial dose).

In adults, when ventricular fibrillation or pulseless VT persists after defibrillation attempts, amiodarone is given as a IV/IO bolus to help stabilize the rhythm by blocking multiple channels and prolonging the heart’s refractory period. The initial dose is 300 mg. If the rhythm remains shockable after additional shocks, a second dose of 150 mg can be given, for a total of up to 450 mg during the arrest. The other listed amounts aren’t the first-dose amount (150 mg is the second-dose amount, 100 mg isn’t standard, and 450 mg reflects the possible total after two doses, not the initial dose).